Can women also have hemophilia?
Severe symptomatic haemophilia is rare but possible in women. Mild symptoms may also occur in women who carry the so-called haemophilia gene. Women may also have other severe bleeding disorders.
How many people with hemophilia are there in Estonia?
There are currently more than a hundred patients with haemophilia in Estonia, almost 90% of whom have a diagnosis of haemophilia A (coagulation factor VIII deficiency). About one-fifth of people with hemophilia are under 18 years of age.
How is hemophilia treated?
The treatment for haemophilia consists of injecting the missing coagulation factor to replace the defective coagulation factor. Each patient’s treatment is different and depends on the severity of their disease and the level of clotting factor in the blood.
What is the prophylactic treatment of hemophilia?
Prophylactic treatment of haemophilia involves the direct introduction of missing coagulation factors into the blood. Prophylactic replacement of coagulation factors prevents, inter alia, spontaneous intra-articular bleeding, which is typical of more severe forms of haemophilia. If not treated quickly and effectively, chronic bleeding can severely damage the joints and cause irreversible damage.
What does primary prevention mean?
Prophylactic treatment is started in early childhood before intra-articular bleeding.
What does secondary prevention mean?
Coagulation factor replacement therapy is started after the onset of 2nd or more bleeding episodes, but before joint damage occurs.
What does tertiary prophylaxis mean?
Prophylactic treatment is started after the development of joint damage
What is on-demand treatment?
The goal of needs-based or bleeding-based treatment is to stop the bleeding quickly by replacing the clotting factor. Acute bleeding should be treated as soon as possible, preferably within 2 hours of the start of the bleeding. The amount depends on the patient’s weight, the location and severity of the bleeding.
How can a person with hemophilia maintain their health better?
Preventive treatment, a healthy lifestyle, physiotherapy and exercise are all important to keep a person with haemophilia healthy. Physiotherapy and exercise help muscles and increase flexibility to help protect and prevent joint bleeds.
Does a person with haemophilia always have to carry the medicine?
Patients with haemophilia should always keep the clotting factor handy. In addition, an emergency card is included with the diagnosis and treatment plan. Before going to the ambulance, you should call the hemophilia treatment center or the emergency hematologist so that we can already pass the information to the emergency department and plan the necessary treatment.
Is every injury life-threatening?
As a rule, small injuries are not dangerous, but they might need longer attention (bandaging, patching) than usual.
Is it possible to cure bleeding disorders?
At present, it is not possible to cure bleeding disorders, but many bleeding disorders can be well-controlled with medical options.
Can people with bleeding disorders live a normal life?
A person with a bleeding disorder who receives proper treatment can live a completely normal life. But it still means following certain rules, for example following your treatment schedule and medical appointment. For contact sports of high trauma risk activites will need better factor coverage.
Can a person with a bleeding disorder be vaccinated against COVID-19?
As with other intramuscular therapies, COVID-19 should be used with caution in subjects with coagulation disorders (eg haemophilia) as bleeding or bruising may occur following intramuscular administration. In more severe bleeding disorders, it is necessary to inject the factor before injecting the vaccine.
What are plasma-based coagulation factor concentrates?
These are coagulation factors produced by the isolation of coagulation proteins from donor blood plasma.
What are recombinant coagulation factor concentrates?
Medicinal products in which the coagulation factor has been prepared synthetically.